Drug of Choice that Used in Infection

Drug of choice is that drug which is known to be most effective in order to cure an infection or disease. A drug of choice should be accessible, cost effective, easily tolerable, safe, and most importantly effective against the disease-causing pathogen.

Following is the list of few of drugs that are used in the common infections.

Dr. Deepak Kumar

Pathogen	Disease	Drug of Choice
Actinomyces	Actinomycosis	Penicillin G
Bacillus anthracis	Anthrax	Ciprofloxacin, Tetracyclines
Bordetella pertussis	Whooping cough	Erythromycin
Borelia burgdorferi	Lyme disease	Tetracycline
Campylobacter	Acute inflammatory diarrhea	Ciprofloxacin
Candida	Vaginal candidiasis Systemic candidiasis	Miconazole Fluconazole
Chlamydia trachomatis	Pelvic inflammatory disease	Doxycycline
Chlamydia pneumonia	Pneumonia	Tetracycline
H. influenza	Pneumonia, Meningitis	3rd Gen Cephalosporin
H. pylori	Gastric ulcers	Metronidazole + Tetracycline
Klebsiella	Pneumonia UTI	3rd Gen Cephalosporin, Quinolones
Legionella	Legionnarie’s disease	Erythromycin
M. Tuberculosis	Tuberculosis	Isoniazid + Rifampin + Pyrazinamide + Ethambutol
M. leprae	Leprosy	Dapsone + Rifampin
M. pneumonia	Atypical pneumonia	Erythromycin
N. gonorrhea	Gonorrhea	Ceftriaxone
N. meningitis	Meningitis	Penicillin G
Nocardia	Pneumonia	Trimethoprim/Sulfamethoxazole
Proteus	UTI	Quinolones
Rickettsia	Spotted fever, Typhus	Tetracycline
Salmonella typhi	Typhoid fever	Ciprofloxacin / Trimethoprim+Sulfamethoxazole
Shigella	Dysentery	Trimethoprim+Sulfamethoxazole
Staph aureus	Skin infection, sepsis, osteomyelitis	Dicloxacillin, nafcillin or oxacillin
Strep. Pyogenes	Pharyngitis, erysipelas	Penicillin G or V
Strep viridans	Endocarditis	Penicillin + Aminoglycoside
Treponema pallidum	Syphilis	Penicillin G
Tropheryma whippelii	Whipple’s disease	Trimethoprim/Sulfamethoxazole
Trichomonas	Trichomoniasis	Metronidazole
Vibrio cholera	Cholera	Tetracycline (+fluids)
Yersinia pestis	Plague (Black death)	Streptomycin