New Solution in The Fight Against Superbugs
New Light-Activated
Nanoparticles Kill Over 90% of Antibiotic-Resistant Bacteria
Bacterial
Resistance to Antibiotics
is a growing Problem around the World,
Responsible
for Some 2 Million Infections in the US each year that lead to approximately
23,000 Deaths.
But a new Nanoparticle
Treatment developed by Researchers at the University of Colorado
Boulder could provide an effective means of Fighting Antibiotic-Resistant Bacteria
including Salmonella, E. coli, and Staphylococcus, based
on Results in a Laboratory Environment.
In testing with
a Lab-Grown Culture, The Nanoparticles killed 92 Percent of Drug-Resistant
Bacterial Cells while leaving the other Cells intact.
The treatment
consists of Light-Activated Nanoparticles called Quantum Dots.
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By shrinking
these Semiconductors down to the Nano scale,
We're Able
to Create Highly Specific Interactions within the Cellular Environment That
Only Target the Infection,"
said Prashant Nagpal, Senior Author of the Study Published in Nature
Materials.
It's not the
first time that Nanoparticles have been used to Combat Bacteria. Previous Research
has shown that Metal Nanoparticles are effective against Antibiotic-Resistant
Infections, But at a Cost indiscriminate Damage caused to Surrounding Cells in
addition to the Infection.
In Contrast,
the Quantum Dots can be tailored to Particular Infections owing to their
Photoexcited (activated by Light) Properties.
The
Nanoparticles are inactive in Darkness, but by exposing them to Particular
Wavelengths of Light, The Researchers Can effectively make the Dots target
Infected Cells.
According to
the Researchers, This Specificity could help Reduce or Eliminate the Side
Effects Patients Experience in Treatments for Infections, and could inform
Future Development of Anti-Bacterial Medicines.
Antibiotics
are not just a Baseline Treatment for Bacterial Infections, but HIV and Cancer
as well. Failure to develop effective Treatments for Drug-Resistant Strains is
not an Option, and that's what this Technology Moves closer to Solving.
There's
obviously a lot More Work to be done before New Technology like this can be
safely used to treat Infections in Humans, but in Light of all the Gloomy
things we tend to hear about Antimicrobial Resistance,
It's Great to
See some Promising News for a Change.
While We can
always count on these Superbugs to adapt and fight the Therapy, We can
quickly tailor these Quantum Dots to come up with a new Therapy and
therefore Fight Back Faster in this Evolutionary Race.