Top 10 Deadliest Outbreaks
Top 10 Deadliest Outbreaks 10. The Smallpox Epidemic of the 1500s During the 1500s, conquerors and colonists invaded the Americas, making it the home of almost 100 million people. The natives, such as the Incas and Aztecs, did not have immune systems that were able to defeat new diseases. These new diseases reduced the population to between 5 and 10 million. Smallpox was caused by the variola virus. The disease caused fevers, body aches and a rash that turns from fluid-filled bumps and scabs into permanent, deep scars. The disease spread through direct contact with infected people's skin or bodily fluids, but could also be contracted through the air in small, confined spaces. Even though the smallpox epidemic during the 1500s was not intentional, there have been instances where the spread of the disease has been a conscious effort to wipe out a population. In 1763, during the French and Indian War, British Commander Sir Jeffrey Amherst instructed the infection of the O...